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肺炎克雷伯菌血清型K2中负责多重耐药的质粒多样性。

Diversity of plasmids responsible for multiple resistance in Klebsiella serotype K2.

作者信息

Richards H, Hughes V, Datta N

出版信息

J Hyg (Lond). 1981 Apr;86(2):189-94. doi: 10.1017/s002217240006890x.

DOI:10.1017/s002217240006890x
PMID:7462603
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2133873/
Abstract

Klebsiella of capsular type K2 were investigated to find out whether a single epidemic clone was the source of many outbreaks of infection in different hospitals, in different areas over a period of five years. The klebsiellas studied were found to be very similar; they were of the same biotype, had similar klebecin sensitivity patterns and carried multiple drug-resistance plasmids; however, characterization of these plasmids showed that they were heterogeneous. Thus there was not a single epidemic bacterial clone.

摘要

对K2荚膜型肺炎克雷伯菌进行了调查,以确定单一的流行克隆是否是五年内不同地区不同医院多次感染暴发的源头。研究发现,所研究的肺炎克雷伯菌非常相似;它们属于同一生物型,具有相似的克雷伯菌素敏感性模式,并携带多重耐药质粒;然而,这些质粒的特征表明它们是异质的。因此,不存在单一的流行细菌克隆。

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本文引用的文献

1
Distribution of genes for trimethoprim and gentamicin resistance in bacteria and their plasmids in a general hospital.某综合医院细菌及其质粒中三甲氧苄氨嘧啶和庆大霉素耐药基因的分布情况
J Gen Microbiol. 1980 Jun;118(2):495-508. doi: 10.1099/00221287-118-2-495.
2
Plasmids and transposons and their stability and mutability in bacteria isolated during an outbreak of hospital infection.医院感染暴发期间分离出的细菌中的质粒、转座子及其稳定性和可变性。
Plasmid. 1979 Apr;2(2):182-96. doi: 10.1016/0147-619x(79)90037-4.
3
The development and assessment of a bacteriocin typing method for Klebsiella.肺炎克雷伯菌细菌素分型方法的开发与评估
J Hyg (Lond). 1979 Apr;82(2):207-23. doi: 10.1017/s0022172400025626.
4
A hospital epidemic caused by gentamicin-resistant Klebsiella aerogenes.由耐庆大霉素产气克雷伯菌引起的医院感染流行。
J Hyg (Lond). 1978 Feb;80(1):115-23. doi: 10.1017/s0022172400053432.
5
A rapid method for the identification of plasmid desoxyribonucleic acid in bacteria.一种鉴定细菌中质粒脱氧核糖核酸的快速方法。
Plasmid. 1978 Sep;1(4):584-8. doi: 10.1016/0147-619x(78)90016-1.
6
Gentamicin-resistant Klebsiella aerogenes in a urological ward.泌尿外科病房中耐庆大霉素的产气克雷伯菌
Lancet. 1977 Aug 27;2(8035):444-6. doi: 10.1016/s0140-6736(77)90621-3.