Poynard T, Alperovitch A
J Radiol. 1980 Aug-Sep;61(8-9):551-6.
The assessment of diagnostic technologies, concerns today both clinicians and health care administrators. This assessment is based upon calculation of various indices measuring the informative value of diagnostic test: sensitivity, specificity, accuracy, predictive value. Despite their extreme semplicity, these indices can be misinterpreted and misused; in addition they are often calculated from very particular patients sample, especially when retrospective data are used. The main points which influence the value confered to a diagnostic test, the major bias to avoid designing such studies are pointed out this paper. The likeness between controlled therapeutic trial and comparative assessment of diagnostic technologies is particularly emphasized.
如今，诊断技术的评估受到临床医生和医疗保健管理人员的关注。这种评估基于对各种衡量诊断测试信息价值的指标的计算：敏感性、特异性、准确性、预测价值。尽管这些指标极其简单，但仍可能被误解和误用；此外，它们往往是根据非常特殊的患者样本计算得出的，尤其是在使用回顾性数据时。本文指出了影响赋予诊断测试价值的要点，以及在设计此类研究时要避免的主要偏差。特别强调了对照治疗试验与诊断技术比较评估之间的相似性。
