Jackaman F R, Perry B J, Siddons H
Thorax. 1978 Dec;33(6):761-3. doi: 10.1136/thx.33.6.761.
In a prospective study of 183 patients undergoing lateral thoracotomy the 125 I fibrinogen uptake test and perioperative heparin prophylaxis for deep-vein thrombosis were investigated. There was an incidence of deep vein thrombosis in 51% in untreated control patients. The heparin prophylaxis effectively reduced the incidence of deep venous thrombosis to 28% (P less than 0.005) without increasing postoperative blood loss. Unilateral thrombosis was found to be significantly more frequent in the leg opposite the side of the thoracotomy (P less than 0.005). The 125I fibrinogen test is essential in assessing methods of prophylaxis but is not recommended as a routine.
在一项对183例行侧开胸手术患者的前瞻性研究中,对125I纤维蛋白原摄取试验及围手术期肝素预防深静脉血栓形成进行了调查。未治疗的对照患者深静脉血栓形成的发生率为51%。肝素预防有效地将深静脉血栓形成的发生率降低至28%(P<0.005),且未增加术后失血量。发现单侧血栓形成在开胸一侧对侧的下肢明显更常见(P<0.005)。125I纤维蛋白原试验在评估预防方法时必不可少,但不建议作为常规检查。