Constantinidis K, Musk A W, Jenkins J P, Berry G
Thorax. 1978 Dec;33(6):764-8. doi: 10.1136/thx.33.6.764.
This retrospective study compares the pulmonary function of 24 coal workers with Caplan's syndrome with that of 36 subjects with non-rheumatoid progressive massive fibrosis (PMF). Allowing for differences in radiographical category, age, years worked underground, and smoking, obstruction to air flow as reflected in the one-second forced expiratory volume, the vital capacity, and the ratio of residual volume to total lung capacity, was significantly less in subjects with Caplan's syndrome. No significant differences in transfer factor were found. These findings may be explained by the different pathological features of the two entities. Selection bias does not appear to be responsible for the differences observed between the groups, but studies designed to eliminate this would be desirable.
这项回顾性研究比较了24例患有卡普兰综合征的煤矿工人与36例患有非类风湿性进行性大块纤维化（PMF）患者的肺功能。考虑到影像学类别、年龄、井下工作年限和吸烟情况的差异，卡普兰综合征患者的一秒用力呼气量、肺活量以及残气量与肺总量之比所反映的气流阻塞程度明显较轻。在肺换气系数方面未发现显著差异。这些发现可能由这两种疾病不同的病理特征来解释。选择偏倚似乎并非导致两组间观察到的差异的原因，但设计旨在消除这种偏倚的研究将是可取的。
