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关于484名有生育能力男性和2768名不育男性的回顾性研究的方法学探讨(作者译)

[Methodological approach of a retrospective study on 484 fertile and 2 768 infertile men (author's transl)].

作者信息

Spira A, Mayaux M J, Schwartz D, Jouannet P, Czyglick F, David G

出版信息

Rev Epidemiol Sante Publique. 1980 Apr 30;28(1):13-20.

PMID:7465908
Abstract

One possible method to study male factors in fertility is the retrospective comparison of groups of fertile and infertile men. Such a study based on 484 fertile and 2 768 infertile men enables us to point out an increasing risk of infertility with decreasing sperm counts and percentage of motile spermatozoa and with increasing abnormal forms. However the increase in relative risk is sharper for the patients who consulted twice or more than those who came for the first time. This difference might in part be explained by the fact that the former had a longer duration of infertility or that the couple infertility had less often a female origin. Consequently detailed information on this subject must be taken into account in studies on fertility.

摘要

研究男性生育因素的一种可能方法是对可育男性和不育男性群体进行回顾性比较。一项基于484名可育男性和2768名不育男性的研究使我们能够指出,随着精子数量、活动精子百分比的降低以及异常形态精子数量的增加,男性不育风险在上升。然而,与首次前来咨询的患者相比,咨询过两次或更多次的患者相对风险增加更为明显。这种差异部分原因可能是前者不育时间更长,或者这对夫妇的不育情况较少由女方因素导致。因此,在生育研究中必须考虑关于这一主题的详细信息。

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