用触珠蛋白-血红蛋白复合物制备并由前列腺素激发的局部类施瓦茨曼现象。
Local Shwartzman-like phenomenon prepared with haptoglobin-hemoglobin complex and provoked with prostaglandin.
作者信息
Shim B S, Kim I K
出版信息
Vox Sang. 1978;35(6):414-9. doi: 10.1111/j.1423-0410.1978.tb02958.x.
Abstract
Intradermal injection of haptoglobin-hemoglobin (Hp-Hb) complex followed by intravenous injection of prostaglandin (PG) F2a or E2 produced a local Shwartzman-like phenomenon (LSLP) in rabbits, whereas PGE1 has no provoking action. Intradermal injection of hemoglobin or erythrocytes also produced LSLP when provoked with endotoxin or PGF2alpha. The provoking action of endotoxin in the local shwartzman reaction may not be entirely mediated through PGs.
摘要
给兔子皮内注射触珠蛋白 - 血红蛋白（Hp - Hb）复合物，随后静脉注射前列腺素（PG）F2α 或 E2，可产生局部施瓦茨曼样现象（LSLP），而前列腺素E1没有激发作用。皮内注射血红蛋白或红细胞，在内毒素或PGF2α激发时也会产生LSLP。内毒素在局部施瓦茨曼反应中的激发作用可能并非完全通过前列腺素介导。
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