Eldridge F L, Millhorn D E, Waldrop T G
Science. 1981 Feb 20;211(4484):844-6. doi: 10.1126/science.7466362.
Unanesthetized decorticate cats walked or ran normally on a treadmill either spontaneously or during electrical stimulation of the subthalamic "locomotor" region. The respiratory response usually preceded the locomotor response and increased in proportion to locomotor activity despite control or ablation of respiratory feedback mechanisms. Respiration increased similarly in paralyzed animals during fictive locomotion despite the absence of muscular contraction or movement. Hypothalamic command signals are thus primarily responsible for the proportional driving of locomotion and respiration during exercise.
未麻醉的去皮质猫在跑步机上能正常行走或奔跑，可自发进行，也可在电刺激丘脑底“运动”区域时进行。呼吸反应通常先于运动反应，且尽管呼吸反馈机制受到控制或被切除，但呼吸反应仍与运动活动成比例增加。在虚构运动期间，尽管没有肌肉收缩或运动，瘫痪动物的呼吸也会同样增加。因此，下丘脑指令信号主要负责运动过程中运动和呼吸的比例驱动。
