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[肾小球肾炎的治疗。免疫抑制与凝血抑制剂——一项比较]

[Glomerulonephritis therapy. Immunosuppression or coagulation inhibitors - a comparison].

作者信息

Schmitt E, Sinn W, Lakner V, Ratner M, Tomilina N

出版信息

Z Gesamte Inn Med. 1980 Aug 1;35(15):Suppl 45-8.

PMID:7467565
Abstract

In 110 patients with mesangioproliferative glomerulonephritis the treatment (n = 48) with chlorambucil, warfarin, dipyridamol and prednisone (CAA) and the treatment with imuran and prednisone (CP, n = 23) are compared with the conditions of an untreated control group. The CAA-therapy is above all suited for active clinical pictures without sclerosis with short duration of the disease, even when the renal function is already restricted. The CP-therapy is suitable in non-active forms with sclerosis also in a longer duration of the disease.

摘要

在110例系膜增生性肾小球肾炎患者中,将苯丁酸氮芥、华法林、双嘧达莫和泼尼松(CAA)治疗组(n = 48)以及硫唑嘌呤和泼尼松治疗组(CP,n = 23)与未治疗的对照组情况进行比较。CAA疗法尤其适用于疾病持续时间短、无硬化的活动性临床表现,即使肾功能已受限。CP疗法适用于疾病持续时间较长、有硬化的非活动性形式。

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