Ahmad K, Cordoba R B, Fayos J V
Arch Otolaryngol. 1981 Jan;107(1):48-51. doi: 10.1001/archotol.1981.00790370050011.
A retrospective analysis of 59 cases of squamous cell carcinoma of the maxillary sinus, which were treated either with radiation alone or combined surgery and radiation, was performed. Fifty-six cases (95%) had T3 and T4 lesions. Our results show that six (66.6%) of nine of T3 and T4 lesions were controlled by combined therapy, while radiation alone controlled 15 (34%) of 44 of T3 and T4 lesions. Five-year actuarial survival of T3 and T4 patients treated with combined therapy was 75% and 33.3%, respectively, while survival of T3 and T4 patients treated with radiation alone was 38.4% and 33.2%, respectively. The five-year actuarial survival for the whole series was 39.3%. It is our opinion that better results could be obtained with surgery followed by radiation therapy in selected cases.
对59例上颌窦鳞状细胞癌患者进行了回顾性分析,这些患者接受了单纯放疗或手术联合放疗。56例(95%)患者存在T3和T4期病变。我们的结果显示,9例T3和T4期病变中有6例(66.6%)通过联合治疗得到控制,而单纯放疗仅控制了44例T3和T4期病变中的15例(34%)。接受联合治疗的T3和T4期患者的5年精算生存率分别为75%和33.3%,而单纯放疗的T3和T4期患者的生存率分别为38.4%和33.2%。整个系列的5年精算生存率为39.3%。我们认为,在某些选定的病例中,先进行手术然后再进行放疗可能会取得更好的效果。