St-Pierre S, Baker S R
Head Neck Surg. 1983 Jul-Aug;5(6):508-13. doi: 10.1002/hed.2890050610.
A retrospective review was performed of 66 patients with squamous cell carcinoma of the maxillary sinus. The majority of patients presented with tumors classified as T3 (31.8%) and T4 (54.5%). Seven (10.6%) patients presented initially with neck metastases and 13 (19.7%) patients subsequently developed regional disease. For the 66 patients studied, the observed 5 and 10 year actuarial survival rate was 27.3% and 20.7% respectively. The presence of cervical metastases, particularly when they developed subsequent to initial therapy, was associated with a poorer survival rate. Five year survival rate for patients without cervical metastases was 32.6% in contrast to 28.6% for patients initially presenting with nodal disease and 7.7% for patients who subsequently developed regional metastases. Overall, 5-year survival rate for all patients with cervical metastases was 15.0%. A combined treatment regimen (surgery and radiation therapy) appeared to be superior to single modality therapy. A 58.0% observed 5-year actuarial survival rate was achieved with combined therapy. Surgery or radiation therapy when used alone as a single modality resulted in a 5-year survival rate of 20.0% and 15.7% respectively.
对66例上颌窦鳞状细胞癌患者进行了回顾性研究。大多数患者的肿瘤分类为T3（31.8%）和T4（54.5%）。7例（10.6%）患者初诊时伴有颈部转移，13例（19.7%）患者随后出现区域病变。在研究的66例患者中，观察到的5年和10年精算生存率分别为27.3%和20.7%。颈部转移的存在，尤其是在初始治疗后出现时，与较差的生存率相关。无颈部转移患者的5年生存率为32.6%，而初诊时有淋巴结疾病的患者为28.6%，随后出现区域转移的患者为7.7%。总体而言，所有有颈部转移患者的5年生存率为15.0%。联合治疗方案（手术和放射治疗）似乎优于单一治疗方式。联合治疗的5年精算生存率为58.0%。单独使用手术或放射治疗作为单一治疗方式时，5年生存率分别为20.0%和15.7%。
