Karal'nik B V, Prokhorova S V, Tsarevskiĭ Iu P
Zh Mikrobiol Epidemiol Immunobiol. 1978 Oct(10):109-14.
The effect on the indication sensitivity of the level of antigenic sensitization of erythrocytes, molecular parameters of sensitin and of the antigen determined was revealed on various models of agglutinates and antigens determined with the aid of erythrocyte deaggregation reaction (EDR). By its dependence on the EDR sensitivity from the hemosensitization level this reaction was analogous to the passive hemagglutination inhibition test described earlier. Specific deaggregation activity of the antigens depended on their molecular parameters in the same way as their specific agglutinating activity in respect to the erythrocytic antibody diagnostic agents--both of these properties were more intensive in larger antigenic molecules.
借助红细胞解聚反应(EDR),在各种凝集物模型和所测定的抗原上,揭示了红细胞抗原致敏水平、敏感素的分子参数以及所测定抗原对指示敏感性的影响。根据其对EDR敏感性与血致敏水平的依赖性,该反应类似于先前描述的被动血凝抑制试验。抗原的特异性解聚活性与其分子参数的关系,与它们对红细胞抗体诊断剂的特异性凝集活性的关系相同——这两种特性在较大的抗原分子中表现得更为强烈。