Hillier K, Smith M D
Br J Obstet Gynaecol. 1981 Mar;88(3):274-7. doi: 10.1111/j.1471-0528.1981.tb00981.x.
The prostaglandins E and F were measured by radioimmunoassay in placentae from 23 normotensive, 25 hypertensive and 13 pre-eclamptic patients. The prostaglandin E levels were respectively (pg/mg +/- SEM) 16.34 +/- 2.06, 16.75 +/- 2.52 and 12.10 +/- 3.63. The prostaglandin F levels were 2.43 +/- 0.41, 2.70 +/- 0.42 and 2.06 +/- 0.31. These prostaglandin concentrations did not differ significantly. Local ischaemia may, therefore, be explained by altered responsiveness to these prostaglandins or to changes in other prostaglandins (such as the vasodilator PGI2) or other vasoactive agents.
通过放射免疫分析法对23名血压正常、25名高血压和13名先兆子痫患者的胎盘进行前列腺素E和F的测定。前列腺素E水平分别为（皮克/毫克±标准误）16.34±2.06、16.75±2.52和12.10±3.63。前列腺素F水平分别为2.43±0.41、2.70±0.42和2.06±0.31。这些前列腺素浓度无显著差异。因此，局部缺血可能是由于对这些前列腺素或其他前列腺素（如血管舒张剂前列环素）或其他血管活性物质反应性改变所致。
