Schwalbe P, Arndt D, Müller-Hermelink H K
Acta Biol Med Ger. 1978;37(7):1105-12.
Water-soluble lymph node extracts and sera from 23 patients with benign and malignant lymphomas and tissue extracts from liver, spleen, kidney, and muscle of one patient without any lymphatic disease were analyzed using the direct leukocyte migration test (LMT). The leukocytes were obtained from healthy persons. 10 of the lymphomas and 3 of the tissue extracts varied the leukocyte migration. In most cases of chronic nonspecific lymphadenitis, in 2 cases of Hodgkin's disease, and in extracts of liver, spleen and muscle inhibitory effects were found. Stimulating effects could be demonstrated in 2 cases of immunocytoma and in 4 cases of Hodgkin's disease. The results indicate that in cases of stimulation the target cells might be influenced by a pathological migration inhibitory factor.
采用直接白细胞迁移试验（LMT）对23例良性和恶性淋巴瘤患者的水溶性淋巴结提取物和血清，以及1例无任何淋巴疾病患者的肝脏、脾脏、肾脏和肌肉组织提取物进行了分析。白细胞取自健康人。10例淋巴瘤和3例组织提取物改变了白细胞迁移。在大多数慢性非特异性淋巴结炎病例、2例霍奇金病病例以及肝脏、脾脏和肌肉提取物中发现了抑制作用。在2例免疫细胞瘤和4例霍奇金病病例中可证明有刺激作用。结果表明，在刺激情况下，靶细胞可能受到病理性迁移抑制因子的影响。
