Joos U, Ochs G, Ries P E
Biomaterials. 1980 Jan;1(1):23-6. doi: 10.1016/0142-9612(80)90053-8.
It can be demonstrated that bone regeneration is stimulated by implantation of Collagenfleece a purified, heterologous collagen preparation. Defects were created in rabbit mandibles which were filled with Collagenfleece on the right side, while the defect on the left side served as a control. The progress in bone regeneration was followed by comparative light and electron microscopic investigations. In contrast to the controls, the defects which were treated with Collagenfleece showed quicker ossification.
可以证明，植入胶原绒（一种纯化的异源胶原制剂）可刺激骨再生。在兔下颌骨上制造缺损，右侧用胶原绒填充，左侧缺损作为对照。通过比较光镜和电镜研究追踪骨再生的进展。与对照组相比，用胶原绒治疗的缺损显示出更快的骨化。
