嗅球切除术后大鼠脑内去甲肾上腺素水平及周转率的变化。

Changes in rat brain norepinephrine levels and turnover after olfactory bulbectomy.

作者信息

Tonnaer J A, Rigter H, Versteeg D H, Nickolson V J

出版信息

Brain Res Bull. 1980 Nov-Dec;5(6):683-6. doi: 10.1016/0361-9230(80)90206-3.

Abstract

After bilateral olfactory bulbectomy in rats a significant increase of norepinephrine (NE) level in the hypothalamus was found. However, no difference was observed between hypothalamic NE turnover of bulbectomized and sham operated animals in the amygdaloid cortex the NE level was not affected by bulbectomy. In this area, however, the NE turnover appeared to be decreased after bulbectomy. The latter finding may be related to the deficits in passive avoidance behaviour as found in bulbectomized rats.

摘要

大鼠双侧嗅球切除术后，发现下丘脑去甲肾上腺素（NE）水平显著升高。然而，嗅球切除组和假手术组动物杏仁核皮质中下丘脑NE周转率没有差异，嗅球切除术未影响NE水平。然而，在该区域，嗅球切除术后NE周转率似乎降低。后一发现可能与嗅球切除大鼠中发现的被动回避行为缺陷有关。