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[心脏病患者的运动测试]

[Exercise testing in cardiac patients].

作者信息

Koike A, Hiroe M, Marumo F

机构信息

2nd Department of Internal Medicine, Tokyo Medical and Dental University.

出版信息

Rinsho Byori. 1995 Aug;43(8):820-7.

PMID:7474442
Abstract

Symptom-limited incremental exercise tests have been used, to estimate the severity of cardiovascular disease and the patients' daily activity. However, there is a considerable amount of interest in obtaining submaximal measurements of aerobic function rather than parameters requiring maximal exercise effort. We compared the parameters obtained during the incremental exercise with those during the 6 minutes of moderate constant work rate exercise. Peak oxygen uptake (VO2) and the anaerobic threshold were significantly decreased in patients with cardiovascular disease as compared to normal subjects. The slope of the increase in carbon dioxide output (VCO2) to the increase in VO2 (delta VCO2/delta VO2) above the anaerobic threshold was significantly increased and the slope of the increase in VO2 to the increase in work rate (delta VO2/delta WR) was significantly decreased in patients with cardiovascular disease. The anaerobic threshold was found to occur at the work rate above which left ventricular function decreased during exercise in these patients. The time constant of VO2 during and following recovery from 6 minutes of 50 watts of constant work rate exercise was significantly longer (the kinetics of VO2 were slower) in patients with cardiovascular disease than in normal subjects. The time constant of VO2 was significantly negatively correlated with peak VO2 and maximum work rate obtained during the incremental exercise.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

症状限制递增运动试验已被用于评估心血管疾病的严重程度和患者的日常活动。然而,人们对获得有氧运动功能的次最大测量值而非需要最大运动强度的参数有着浓厚兴趣。我们比较了递增运动期间与中等恒定工作率运动6分钟期间获得的参数。与正常受试者相比,心血管疾病患者的峰值摄氧量(VO2)和无氧阈值显著降低。心血管疾病患者无氧阈值以上二氧化碳排出量增加(VCO2)与VO2增加(ΔVCO2/ΔVO2)的斜率显著增加,VO2增加与工作率增加(ΔVO2/ΔWR)的斜率显著降低。发现这些患者的无氧阈值出现在运动期间左心室功能下降的工作率之上。心血管疾病患者在50瓦恒定工作率运动6分钟期间及恢复后的VO2时间常数显著更长(VO2动力学更慢)。VO2时间常数与递增运动期间获得的峰值VO2和最大工作率显著负相关。(摘要截断于250字)

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