Search of hidden periodicities in DNA sequences.

The hidden periodicities in various genomes can be identified via a Fourier transform of genomic DNA sequences. The typical search strategies are described and the corresponding statistical criteria are presented. The methods are applied to the structural analysis of genome for bacteriophage PHIX174. The results indicate the important role of the coherent structural modifications along the several main periods in the formation of the genome. Some possible mechanisms for the features observed are discussed.