Platel K, Srinivasan K
Department of Biochemistry & Nutrition, Central Food Technological Research Institute, Mysore, India.
Nahrung. 1995;39(4):262-8. doi: 10.1002/food.19950390403.
Consumption of bitter gourd (Momordica charantia) by diabetic patients is a common practice in India, with the belief that it has an useful hypoglycemic potential. In the absence of conclusive information on the hypoglycemic influence of continuous intake of bitter gourd, in the present investigation, we have examined the hypoglycemic potency of dietary bitter gourd in experimentally induced diabetic rats. Wistar rats rendered hyperglycemic by streptozotocin (50 mg/kg b.w., i.p.) were maintained on a semi-synthetic diet containing freeze dried bitter gourd powder at 0.5% level for 6 weeks. The excretion of glucose, protein, urea and creatinine was monitored during the experimental period. Plasma glucose, albumin, urea and cholesterol were analysed at the end of the experimental regime. Dietary bitter gourd did not show any beneficial hypoglycemic influence as evidenced by the blood glucose levels as well as the excretion of diabetes related metabolites.
糖尿病患者食用苦瓜（苦瓜属）在印度是一种常见做法，人们认为苦瓜具有有益的降血糖潜力。由于缺乏关于持续摄入苦瓜的降血糖影响的确切信息，在本研究中，我们检测了实验性诱导糖尿病大鼠食用膳食苦瓜的降血糖效力。通过链脲佐菌素（50毫克/千克体重，腹腔注射）使Wistar大鼠血糖升高，然后让它们在含0.5%冻干苦瓜粉的半合成饮食中维持6周。在实验期间监测葡萄糖、蛋白质、尿素和肌酐的排泄情况。在实验结束时分析血浆葡萄糖、白蛋白、尿素和胆固醇。血糖水平以及糖尿病相关代谢物的排泄情况表明，膳食苦瓜未显示出任何有益的降血糖影响。
