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与适应温暖环境的仓鼠和大鼠相比,冬眠的土耳其仓鼠海马切片在低温下的长时程增强作用更强。

Long-term potentiation at low temperature is stronger in hippocampal slices from hibernating Turkish hamsters compared to warm-acclimated hamsters and rats.

作者信息

Spangenberger H, Nikmanesh F G, Igelmund P

机构信息

Zentrum Physiologie und Pathophysiologie der Universität zu Köln, Germany.

出版信息

Neurosci Lett. 1995 Jul 14;194(1-2):127-9. doi: 10.1016/0304-3940(95)11723-a.

DOI:10.1016/0304-3940(95)11723-a
PMID:7478194
Abstract

Tetanus-induced long-term potentiation (LTP) of population action potentials at 22 degrees C was investigated in area CA1 of hippocampal slices prepared from hibernating (HH) and warm-acclimated Turkish hamsters (WH) and rats. LTP elicited at this temperature was significantly stronger in HH slices compared to WH and rat slices. Hibernation-related improvement of the ability to develop long-lasting enhancement of synaptic transmission at low temperatures is interpreted as supporting hippocampal function during arousal from hibernation.

摘要

在22摄氏度下,对从冬眠的(HH)、暖适应的土耳其仓鼠(WH)和大鼠制备的海马切片CA1区中群体动作电位的破伤风诱导长期增强(LTP)进行了研究。与WH和大鼠切片相比,在该温度下诱导的LTP在HH切片中明显更强。低温下突触传递产生持久增强能力的冬眠相关改善被解释为在从冬眠中苏醒时支持海马功能。

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