Johnston Celeste C, Stevens Bonnie J, Yang Fang, Horton Linda
McGill University School of Nursing, Montreal, Canada Montreal Children's Hospital, Montreal, Canada University of Toronto, Faculty of Nursing, Toronto, Canada Mt. Sinai Hospital Perinatal Nursing Research Unit, Toronto, Canada Royal Victoria Hospital, Premature Nursery, Montreal, Canada.
Pain. 1995 Jun;61(3):471-479. doi: 10.1016/0304-3959(94)00213-X.
The ability of very low birth weight (VLBW) premature infants to respond differentially to real versus a sham heelstick conditions was examined in this crossover study. Using a multidimensional assessment of responses of premature infants (n = 48) between 26 and 31 weeks gestational age (GA) at the time of the study, it was found that they respond differentially to real versus sham heelstick both behaviourally and physiologically. The multivariate effect of condition (real/sham) was significant with maximum heart rate and upper facial action (lower facial action was not scored) contributing significantly to the main effect. GA had a main multivariate effect, with the younger infants responding less robustly. The variability outcome measures of heart rate standard deviation and range of transfontanelle intracranial pressure contributed significantly to the main effect of GA, but not to the effect of condition. Young VLBW premature infants are capable of a multidimensional differential response to pain. GA is an important factor to consider when assessing pain in premature infants.
在这项交叉研究中，研究了极低出生体重（VLBW）早产儿对真实足跟采血与假足跟采血情况做出不同反应的能力。通过对研究时孕龄（GA）在26至31周之间的早产儿（n = 48）的反应进行多维度评估，发现他们在行为和生理上对真实足跟采血与假足跟采血的反应不同。状态（真实/假）的多变量效应显著，最大心率和上脸部动作（未对下脸部动作进行评分）对主要效应有显著贡献。孕龄有主要的多变量效应，年龄较小的婴儿反应不那么强烈。心率标准差和前囟颅内压范围的变异性结果指标对孕龄的主要效应有显著贡献，但对状态效应没有贡献。极低出生体重的早产婴儿能够对疼痛做出多维度的不同反应。在评估早产儿的疼痛时，孕龄是一个需要考虑的重要因素。
