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白塞病:一例伴有咯血、假性脑瘤和动脉炎的病例。

Behçet's disease: a case with hemoptysis, pseudotumor cerbri, and arteritis.

作者信息

Reza M J, Demanes D J

出版信息

J Rheumatol. 1978 Fall;5(3):320-6.

PMID:748557
Abstract

A case of Behçet's diease with massive hemoptyis is described. The hemoptysis occurred during disease exacerbation with extensive oropharyngeal and laryngeal ulcerations, and responded to high-dose corticosteroid therapy. Other unusual manifestations included a light sensitive dermatitis, pseudotumor cerebri, and right bundle branch block. Also, arteritis and subsequent occlusion of the femoral and popliteal arteries occurred. Although uncommon, pumonary involvement may be life-threatening and should be treated with corticosteroids. Both pulmonary and neurologic involvement tend to occur with active aphthosis and respond to corticosteroids. This case underscores the protean nature of the organ system involvement in Behçet's disease and supports the concept that vasculitis is a primary pathophysiologic event.

摘要

本文描述了一例伴有大量咯血的白塞病病例。咯血发生在疾病加重期,伴有广泛的口咽和喉部溃疡,对大剂量皮质类固醇治疗有反应。其他不寻常的表现包括光敏性皮炎、假性脑瘤和右束支传导阻滞。此外,还发生了动脉炎以及随后的股动脉和腘动脉闭塞。虽然不常见,但肺部受累可能危及生命,应使用皮质类固醇进行治疗。肺部和神经系统受累往往与活动性口疮病同时发生,且对皮质类固醇有反应。该病例强调了白塞病累及器官系统的多样性,并支持血管炎是主要病理生理事件这一概念。

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