Benhalima B, Cohen A, Chauvel C, Abergel E, Albo C, Elhadad S, Hoebeiche M, Khireddine M, Rozensztajn L, Valty J
Service de cardiologie, hôpital Saint-Antoine, Paris.
Arch Mal Coeur Vaiss. 1995 Mar;88(3):345-52.
Ruptured mitral chordae tendinae is a classical complication of myxomatous mitral valves or Barlow's syndrome. This complication is controversial in non-myxomatous mitral valve. Of 91 consecutive patients with mitral valve prolapse examined over an 18 months period by transthoracic and transesophageal echocardiography, 42 (18 women and 24 men) with an average age of 76 +/- 8 years (60-93 years) had ruptured mitral chordae tendinae. The thickness of the anterior mitral leaflet measured at the distal third of the valve by transesophageal echocardiography enabled the identification of two groups of patients; group I: > 3 mm (24 patients), average 4.8 +/- 0.8 mm and group II: < or = 3 mm (18 patients), average 2.6 +/- 0.3 mm. The diameter of the mitral ring and left atrium, the length of the anterior mitral leaflet, the left ventricular end diastolic dimensions and fractional shortening, were measured by transthoracic 2D echocardiography (mitral ring) and M mode (other parameters). Ruptured chordae were detected in only 13 cases (31%) by transthoracic echocardiography; 38% were asymptomatic and a chance finding at transesophageal echocardiography. No significant difference was observed between the two groups with respect to age, gender presence of hypertension, dimensions of the cardiac chambers, fractional shortening or localisation of the prolapse related to the ruptured chordae. Fifty-eight per cent of patients in group I were in NYHA functional classes 3-4 as compared to 16% in group II (p < 0.02). The size of the left atrium was significantly greater in group I, 51 +/- 8 mm vs 38 +/- 7 mm (p < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
二尖瓣腱索断裂是黏液瘤样二尖瓣或巴洛综合征的典型并发症。这种并发症在非黏液瘤样二尖瓣中存在争议。在18个月期间,通过经胸和经食管超声心动图对91例连续的二尖瓣脱垂患者进行检查,其中42例(18名女性和24名男性)平均年龄为76±8岁(60 - 93岁)发生了二尖瓣腱索断裂。经食管超声心动图在瓣膜远端三分之一处测量二尖瓣前叶厚度,据此可将患者分为两组;第一组:>3mm(24例患者),平均4.8±0.8mm;第二组:≤3mm(18例患者),平均2.6±0.3mm。通过经胸二维超声心动图(二尖瓣环)和M型超声(其他参数)测量二尖瓣环和左心房直径、二尖瓣前叶长度、左心室舒张末期内径和缩短分数。经胸超声心动图仅在13例(31%)中检测到腱索断裂;38%无症状,是经食管超声心动图偶然发现的。两组在年龄、性别、高血压存在情况、心腔大小、缩短分数或与断裂腱索相关的脱垂定位方面未观察到显著差异。第一组58%的患者处于纽约心脏协会功能分级3 - 4级,而第二组为16%(p<0.02)。第一组左心房大小明显更大,51±8mm对38±7mm(p<0.001)。(摘要截断于250字)