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特异性IgE在马来西亚过敏性鼻炎患者变应原鉴定中的应用

Specific IgE in the identification of allergens in allergic rhinitis Malaysian patients.

作者信息

Choon-Kook S, Teck-Soong S L

机构信息

Institute of Advanced Studies, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Asian Pac J Allergy Immunol. 1995 Jun;13(1):23-7.

PMID:7488340
Abstract

The specific serum IgE levels to 20 allergens were determined by enzyme immunoassay in 90 Malaysian patients with allergic rhinitis. Ninety-two percent of patients had elevated IgE to at least 1 of the allergens. The housedust mites D. pteronyssinus and D. farinae were the major allergens, elevated IgE to either allergen being present in 86% of the patients. Prick skin tests were carried out in some of the patients, housedust mites, cat fur, dog hair and shrimp were the allergens used. Close correspondence was found between IgE and prick skin tests to the mites.

摘要

采用酶免疫分析法测定了90例马来西亚过敏性鼻炎患者针对20种变应原的特异性血清IgE水平。92%的患者针对至少1种变应原的IgE水平升高。屋尘螨中的粉尘螨和户尘螨是主要变应原,86%的患者针对其中任一变应原的IgE水平升高。对部分患者进行了点刺皮肤试验,所用变应原包括屋尘螨、猫毛、狗毛和虾。发现针对螨的IgE水平与点刺皮肤试验结果之间存在密切相关性。

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