Bañuelos Arias Alejandra del Carmen, Montaño Velázquez Bertha Beatriz, Campillo Navarrete Martín Ramón, Mojica Martínez María Dolores, Ayala Balboa Julio César, Silva Vera Rosalía Isabel, Cisneros Salazar María del Refugio, Becerril Angeles Martín, Ruiz Hinojosa Arturo, Jáuregui Renaud Kathrine
Departamento de Otorrinolaringología del Hospital General Dr. Gaudencio González Garza, México, DF.
Rev Alerg Mex. 2003 Jul-Aug;50(4):147-53.
Skin tests are the most used diagnostic method of allergic rhinitis, which, in addition to identify specific allergen, can determine the relative sensitivity of one patient to the allergen.
To assess the association between skin test reactivity and total and specific serum IgE levels on the diagnosis of patients with perennial allergic rhinitis.
We measured the response to skin test reactivity and total and specific serum IgE levels in 69 patients with perennial allergic rhinitis.
The skin test reactivity showed responses to: Dermatophagoides pt in 62 patients (90%), house dust in 57 (83%), cat in 41 (59%), dog in 23 (33%), and Lolium p in 16 (23%). The mean level of total IgE was of 378 UI (19 to 4,036) and that of specific IgE was of 39.2 UI (0.2 to 98.6). Total IgE > 200 UI was observed in fifty two patients (75%), which was significantly lesser than the frequency of specific IgE > 0.35 UI (at least for an allergen), which was 94% (p < 0.05, Z). At least two tests of skin reactivity were positive for 90% of the patients. This frequency was similar to the 95% for the specific IgE but different to the 75% for the total IgE (p < 0.05, X2). The correlation between the results of the skin test reactivity and the specific seric IgE showed Spearman r from 0.23 to 0.35 (p < 0.05). The correlation between the total IgE and the specific IgE showed a Spearman r of 0.08 (p < 0.05) and between the total IgE and the skin test reactivity an r of 0.15 (p < 0.05).
In the diagnosis of perennial allergic rhinitis, the results of the skin test reactivity and the specific serum IgE are correlated but these two results are non consistent with the results of the total serum IgE.
皮肤试验是变应性鼻炎最常用的诊断方法，除了识别特定变应原外，还能确定患者对该变应原的相对敏感性。
评估皮肤试验反应性与血清总IgE和特异性IgE水平在常年性变应性鼻炎患者诊断中的相关性。
我们检测了69例常年性变应性鼻炎患者的皮肤试验反应性以及血清总IgE和特异性IgE水平。
皮肤试验反应性显示对以下变应原产生反应：62例（90%）对粉尘螨、57例（83%）对屋尘、41例（59%）对猫、23例（33%）对狗、16例（23%）对黑麦草产生反应。血清总IgE平均水平为378 UI（19至4036），特异性IgE平均水平为39.2 UI（0.2至98.6）。52例患者（75%）血清总IgE>200 UI，这显著低于特异性IgE>0.35 UI（至少对一种变应原）的频率，后者为94%（p<0.05，Z检验）。90%的患者至少两项皮肤反应性试验呈阳性。该频率与特异性IgE的95%相似，但与血清总IgE的75%不同（p<0.05，卡方检验）。皮肤试验反应性结果与血清特异性IgE之间的相关性显示Spearman相关系数r为0.23至0.35（p<0.05）。血清总IgE与特异性IgE之间的相关性显示Spearman相关系数r为0.
