[布良斯克州患甲状腺疾病儿童淋巴细胞中染色体畸变的频率]

[The frequency of chromosome aberrations in the lymphocytes of children with thyroid diseases living in Bryansk Province].

作者信息

Khandogina E K, Zvereva S V, Ageĭkin V A, Marchenko L F, Shakhtarin V V, Mutovin G R, Akif'ev A P

出版信息

Radiats Biol Radioecol. 1995 Sep-Oct;35(5):626-30.

Abstract

The number of unstable chromosome aberrations was determined in peripheral blood lymphocytes from 15 children with thyreopathology living in Klintsy (Bryansk Province); the mean age was 14 years. The number of dicentric chromosome is determined to be (0.18 +/- 0.07) per 100 cells and is significantly higher than that in cells from healthy children of Klintsy and Moscow (control). There was no differences in the frequency of other types of chromosome aberrations as well as of aberrant cells.

摘要

对居住在克林齐（布良斯克州）的15名患有甲状腺疾病的儿童外周血淋巴细胞中的不稳定染色体畸变数量进行了测定；平均年龄为14岁。双着丝粒染色体的数量测定为每100个细胞中有(0.18±0.07)个，显著高于克林齐和莫斯科健康儿童（对照组）细胞中的数量。其他类型染色体畸变以及畸变细胞的频率没有差异。

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