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[布良斯克州放射性污染地区儿童免疫指标(抗微粒体抗体)和细胞遗传学指标的比较研究]

[A comparative study of the immunological (antimicrosomal antibodies) and cytogenetic indices of children living in radioactively contaminated areas of Bryansk Province].

作者信息

Shinkarkina A P, Zhloba A A, Podgorodnichewnko V K, Sevan'kaev A V, Poverennyĭ A M

出版信息

Radiats Biol Radioecol. 1997 May-Jun;37(3):404-7.

PMID:9244530
Abstract

The chromosome dicentric aberrations in the lymphocytes and levels of antibodies to human thyroid microsomal antigen in the serum of the children lived in the area of Bryansk Province suffered from the Chernobyl accident was examined. Correlation between those tests was not estimated: the autoantibodies were revealed in group with dicentrics and without those in 4.0% and 4.5% of cases correspondingly. Antimicrosomal antibodies were revealed more frequently (5.0%) and in higher titers in the children from the more polluted Bryansk Province than in those from Kaluga Province (3.1%). These data can testify about the role of inside radiation of thyroid gland in appearance of autoimmune thyroiditis signs.

摘要

对生活在布良斯克州受切尔诺贝利事故影响地区的儿童淋巴细胞中的染色体双着丝粒畸变及血清中抗人甲状腺微粒体抗原抗体水平进行了检测。未评估这些检测之间的相关性:在有双着丝粒的组和无双着丝粒的组中,自身抗体的检出率分别为4.0%和4.5%。与卡卢加州的儿童相比,来自污染更严重的布良斯克州的儿童抗微粒体抗体检出率更高(5.0%)且滴度更高(3.1%)。这些数据可以证明甲状腺内辐射在自身免疫性甲状腺炎体征出现中的作用。

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