[精神分裂症患者淋巴细胞中的放射适应性反应]
[The radioadaptive response in the lymphocytes of schizophrenia patients].
作者信息
Tskhovrebova L V, Makedonov G P, L'vova G N, Chekova V V, Maksimova T N, Zasukhina G D
出版信息
Radiats Biol Radioecol. 1995 Sep-Oct;35(5):665-9.
PMID:7489100
Abstract
Radioadaptive response in cells from three patients was studied by induction of structural chromosome aberrations. Radioadaptive response was revealed in lymphocytes of all three patients. Coefficient of protection was 59.0% and did not differ from this after cell pretreatment with interferon. It is suggested the similarity or identity of mechanism of radioadaptive response and of interferon antimutagenic action which was implemented by non-repair way.
摘要
通过诱导结构性染色体畸变，研究了三名患者细胞中的辐射适应性反应。在所有三名患者的淋巴细胞中均发现了辐射适应性反应。保护系数为59.0%，与用干扰素预处理细胞后的保护系数无差异。提示辐射适应性反应机制与通过非修复途径实现的干扰素抗诱变作用机制相似或相同。
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