Trubel W, Schima H, Moritz A, Raderer F, Windisch A, Ullrich R, Windberger U, Losert U, Polterauer P
Department of Vascular Surgery, University of Vienna, School of Medicine, Austria.
Eur J Vasc Endovasc Surg. 1995 Nov;10(4):415-23. doi: 10.1016/s1078-5884(05)80163-7.
Compliance and formation of distal anastomotic intimal hyperplasia (DAIH) were investigated in externally stiffened venous grafts of varying calibers.
36 femoropopliteal reconstructions were performed in 18 sheep. The autologous venous grafts were inserted into tubes made of Dacron mesh to achieve compliance-mismatch and lumen adaptation. Compliance was measured by echotracked ultrasonography and profiles of DAIH were generated from histologic sections harvested after 8.3 months.
The external mesh tube significantly lowered the local compliance of graft and host artery. DAIH appeared extensively in those groups where mesh tube constricted venous grafts met untreated host arteries (p = 0.002). No differences in compliance and DAIH formation were observed when grafts with large and adapted diameters were compared.
For prevention of DAIH the distal venous graft diameter is not important, while the local compliance of an autologous vein is a predictive factor for DAIH formation and thus long-term patency.
研究不同管径的外部加固静脉移植物中远端吻合口内膜增生（DAIH）的顺应性和形成情况。
对18只绵羊进行了36次股腘动脉重建。将自体静脉移植物插入由涤纶网制成的管中，以实现顺应性不匹配和管腔适配。通过超声跟踪超声检查测量顺应性，并从8.3个月后采集的组织学切片生成DAIH的轮廓。
外部网网管显著降低了移植物和宿主动脉的局部顺应性。在网网管收缩静脉移植物与未处理的宿主动脉相遇的那些组中，DAIH广泛出现（p = 0.002）。当比较直径大且适配的移植物时，未观察到顺应性和DAIH形成的差异。
为预防DAIH，远端静脉移植物直径并不重要，而自体静脉的局部顺应性是DAIH形成及长期通畅的预测因素。
