Ferreiro J A, Myers J L, Bostwick D G
Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN 55905, USA.
Mayo Clin Proc. 1995 Dec;70(12):1137-41. doi: 10.4065/70.12.1137.
To determine the accuracy of frozen section examination for routine diagnostic use in surgical pathology.
We retrospectively reviewed the experience with frozen sections at Mayo Clinic Rochester during calendar year 1993.
The results in 24,880 cases (97,914 frozen section slides) processed during 1993 were compared with findings on permanent sections, and types of errors detected were classified into one of three quality assurance categories.
The overall rate of frozen section accuracy was 97.8%. Of the 2.2% of surgical pathology reports that needed revision, 1.6% were unavoidable tissue sampling errors, 0.5% were errors that reflected change in degree of abnormality, and only 0.1% were clinically significant errors that may have affected patient management.
Frozen section diagnosis is accurate for processing a high volume of surgical pathology cases.
确定冰冻切片检查在外科病理学常规诊断中的准确性。
我们回顾性分析了梅奥诊所罗切斯特院区1993年全年的冰冻切片检查经验。
将1993年处理的24,880例病例（97,914张冰冻切片）的结果与石蜡切片的结果进行比较，并将检测到的错误类型归类为三个质量保证类别之一。
冰冻切片检查的总体准确率为97.8%。在需要修订的2.2%的外科病理学报告中，1.6%是不可避免的组织采样错误，0.5%是反映异常程度变化的错误，只有0.1%是可能影响患者治疗的具有临床意义的错误。
冰冻切片诊断对于处理大量外科病理学病例是准确的。
