Couderc P, Phelip X, Mouries D, Gras J P, Pasquier D, Cabanel G
Rev Rhum Mal Osteoartic. 1978 Dec;45(12):703-6.
The study of 25 samples of synovial membrane taken from 118 subjects with articular chondrocalcinosis makes it possible to identify three histological aspects : the complete forms showing a crystalline deposit of calcium pyrophosphate of variable volume and alterations of an inflammatory or degenerative type ; incomplete forms showing no calcium deposit, but in which one can observe two sorts of modifications : forms of chondroid metamorphism or inflammatory stigmatas causing an indeterminate chronic synovitis ; finally, forms of superficial fibrosis of the chorion are sometimes encountered. In all, the synovial membrane in articular chodrocalcinosis is often little different from an arthrosic or senile one. However, the presence of crystalline deposits rich in calcium and phosphorous and varying in size can, in the face of certain articular manifestations of uncertain cause, point to the existence of an articular chondrocalcinosis.
对取自118例关节软骨钙质沉着症患者的25份滑膜样本进行研究，可识别出三种组织学表现：完全型表现为焦磷酸钙晶体沉积，体积不一，并伴有炎症或退行性改变；不完全型无钙沉积，但可观察到两种改变：软骨样化生形式或炎症特征导致的不确定慢性滑膜炎；最后，有时会遇到绒毛膜浅层纤维化形式。总之，关节软骨钙质沉着症中的滑膜通常与关节炎性或老年性滑膜差别不大。然而，面对某些病因不明的关节表现时，存在富含钙和磷且大小各异的晶体沉积可提示关节软骨钙质沉着症的存在。
