Perederiĭ O F, Morozova R P
Ukr Biokhim Zh (1978). 1978 Nov-Dec;50(6):777-82.
The contents of squalene, free and esterified sterols (metastenol, lathosterol, 7-dehydrocholesterol, cholesterol) in tissues of the rat esophageal and glandular stomach were studied in normalcy and under the effect of acetyl salicylic acid. The tissue of different stomach regions differs in the content of squalene, free and esterified sterols. Under the effect of acetyl salicylic acid the content of squalene and free sterols in tissues of the both stomach regions lowers. The amount of esterified sterols rises in the tissue of glandular stomach and lowers in the tissue of esophageal region. The data obtained are discussed taking into account the function of sterols in biological membranes.
研究了正常情况下以及乙酰水杨酸作用下大鼠食管和腺胃组织中角鲨烯、游离和酯化甾醇(变肾上腺素、羊毛甾醇、7-脱氢胆固醇、胆固醇)的含量。不同胃区域的组织在角鲨烯、游离和酯化甾醇含量上存在差异。在乙酰水杨酸作用下,两个胃区域组织中的角鲨烯和游离甾醇含量降低。腺胃组织中酯化甾醇的量增加,而食管区域组织中酯化甾醇的量减少。结合甾醇在生物膜中的功能对所得数据进行了讨论。