Barker-Cummings C, McClellan W, Soucie J M, Krisher J
Department of Epidemiology, Emory University, Atlanta, GA 30322, USA.
JAMA. 1995 Dec 20;274(23):1858-62.
To evaluate the influence of ethnicity on the use of peritoneal dialysis (PD) as initial treatment for end-stage renal disease (ESRD) after controlling for other patient characteristics.
Inception cohort analysis of incident ESRD patients.
All African-American and white patients (N = 10,726) who began treatment for ESRD at dialysis centers in North Carolina, South Carolina, and Georgia and reported to ESRD Network 6 between January 1, 1989, and December 31, 1991.
Odds ratios (ORs) of the association between ethnicity and PD as initial treatment modality.
African-American patients were 56% less likely than whites to use PD (OR, 0.44; 95% confidence interval [CI], 0.40 to 0.49). This difference persisted (OR, 0.45; 95% CI, 0.38 to 0.52) after multivariable adjustment for age, education, social support, home ownership, functional status, albumin level, hypertension, history of myocardial infarction, peripheral neuropathy, and comorbid diabetes.
Ethnic differences in initial PD use cannot be explained by many demographic, socioeconomic, and comorbid factors associated with the use of PD as initial treatment for ESRD.
在控制其他患者特征后，评估种族对终末期肾病（ESRD）初始治疗采用腹膜透析（PD）的影响。
对新发ESRD患者进行起始队列分析。
1989年1月1日至1991年12月31日期间在北卡罗来纳州、南卡罗来纳州和佐治亚州的透析中心开始接受ESRD治疗并向ESRD网络6报告的所有非裔美国人和白人患者（N = 10726）。
种族与作为初始治疗方式的PD之间关联的比值比（OR）。
非裔美国患者采用PD的可能性比白人低56%（OR，0.44；95%置信区间[CI]，0.40至0.49）。在对年龄、教育程度、社会支持、住房所有权、功能状态、白蛋白水平、高血压、心肌梗死病史、周围神经病变和合并糖尿病进行多变量调整后，这种差异仍然存在（OR，0.45；95% CI，0.38至0.52）。
初始PD使用中的种族差异无法用许多与将PD作为ESRD初始治疗相关的人口统计学、社会经济和合并症因素来解释。
