Rosati P
Istituto di Clinica Ostetrica e Ginecologica, Università Cattolica del Sacro Cuore, Roma.
Radiol Med. 1995 Sep;90(3):269-71.
Thirty-six pregnant women with a single uterine myoma were submitted to US at 2 and 4 weeks' intervals. The first US examination was made in 12 patients before pregnancy and in the other 24 patients between 9 and 12 weeks' gestation. The changes in the volume of myomas were analyzed in different periods of pregnancy. Thirty-four women underwent US in puerperium, four weeks after delivery: the myomas were smaller, possibly back to their initial volume. In 11 patients (31.6%), the myomas grew bigger during pregnancy, particularly during the first trimester. A statistically significant change in volume was observed between the first and the third trimester of pregnancy (p < 0.001). When investigating myoma growth in greater detail in the first trimester, we observed that the greatest increase in myoma volume occurred before the 10th gestational week. Three different categories of myoma volume were considered (p < 100 cc, 100-200 cc, > 200 cc) and related to myoma growth in each period. No relationship was observed between myoma volume and myoma growth.
36例患有单个子宫肌瘤的孕妇每隔2周和4周接受一次超声检查。首次超声检查在12例患者妊娠前进行，另外24例患者在妊娠9至12周期间进行。分析了妊娠不同时期肌瘤体积的变化。34名妇女在产后四周的产褥期接受了超声检查：肌瘤变小，可能恢复到初始体积。11例患者（31.6%）的肌瘤在孕期增大，尤其是在孕早期。在妊娠的第一个和第三个三个月之间观察到体积有统计学上的显著变化（p<0.001）。当在孕早期更详细地研究肌瘤生长时，我们观察到肌瘤体积的最大增加发生在妊娠第10周之前。考虑了三种不同类别的肌瘤体积（p<100 cc、100 - 200 cc、>200 cc），并将其与每个时期的肌瘤生长相关联。未观察到肌瘤体积与肌瘤生长之间的关系。
