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孕期子宫肌瘤生长的纵向评估:一项超声研究

Longitudinal evaluation of uterine myoma growth during pregnancy. A sonographic study.

作者信息

Rosati P, Exacoustòs C, Mancuso S

机构信息

Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy.

出版信息

J Ultrasound Med. 1992 Oct;11(10):511-5. doi: 10.7863/jum.1992.11.10.511.

DOI:10.7863/jum.1992.11.10.511
PMID:1404579
Abstract

Thirty-six pregnant women with a single uterine myoma were examined by ultrasonography at 2 to 4 week intervals. The initial diagnosis was made in 12 patients before pregnancy and in the other 24 patients between 9 and 12 weeks of gestation. Thirty-four women had a scan 4 weeks after delivery. A reduction in size was observed in puerperium, which may indicate a return to its initial volume. Myoma growth was analyzed in different periods of gestation. An increase in volume during pregnancy was observed in 31.6% of cases. A statistically significant change in volume was noted between the first and the third trimesters (P < 0.001). The greatest increase in volume of myomas occurred before the 10th week of gestation. The relationship between myoma volume and myoma growth in the different gestational periods considered was not statistically significant. On the other hand, when myoma volume was related to complications during pregnancy or at delivery, a statistically significant difference was observed. Myomas with volumes greater than 200 cm3 show a higher rate of complications than those with volumes equal to or less than 100 cm3.

摘要

对36名单发子宫肌瘤的孕妇每隔2至4周进行超声检查。12例患者在孕前确诊,另外24例在妊娠9至12周时确诊。34名女性在产后4周进行了扫描。观察到产后肌瘤体积缩小,这可能表明其恢复到初始体积。分析了妊娠不同时期肌瘤的生长情况。31.6%的病例在孕期肌瘤体积增大。在孕早期和孕晚期之间观察到肌瘤体积有统计学上的显著变化(P<0.001)。肌瘤体积在妊娠第10周前增加最多。所考虑的不同孕期肌瘤体积与肌瘤生长之间的关系无统计学意义。另一方面,当肌瘤体积与妊娠期间或分娩时的并发症相关时,观察到有统计学上的显著差异。体积大于200cm³的肌瘤比体积等于或小于100cm³的肌瘤并发症发生率更高。

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