Błaszczyk B, Stobiecki M, Kowalczyk-Bronisz S H, Gulewicz K, Szymaniec S
Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Arch Immunol Ther Exp (Warsz). 1994;42(2):147-53.
The results demonstrated immunotropic activity of seeds extracts and fractions from Lupinus angustifolius and Lupinus albus. Plaque forming cells (PFC) number to SRBC (sheep red blood cells) were elevated by an extract from Lupinus angustifolius and lowered by extracts from Lupinus albus. All preparations obtained from Lupinus angustifolius reduced the number of rosette forming cells (E-RFC). These preparations suppressed also the intensity of graft versus host reaction (GVHR) in case when the donors were treated. Lupinus albus extract suppressed GVH reaction when recipients were treated. Lupin extracts stimulated draining popliteal lymph nodes in PLN assay.
结果表明，窄叶羽扇豆和白羽扇豆种子提取物及馏分具有免疫调节活性。窄叶羽扇豆提取物可提高对绵羊红细胞（SRBC）的空斑形成细胞（PFC）数量，而白羽扇豆提取物则使其降低。从窄叶羽扇豆获得的所有制剂均减少了玫瑰花结形成细胞（E-RFC）的数量。当供体接受处理时，这些制剂还抑制了移植物抗宿主反应（GVHR）的强度。当受体接受处理时，白羽扇豆提取物可抑制GVH反应。羽扇豆提取物在PLN试验中刺激引流腘淋巴结。
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