Metzger J O, Woisch R, Tuszynski W, Angermann R, Puls J
Department of Chemistry, Carl von Ossietzky-Universität, Oldenburg, Germany.
Rapid Commun Mass Spectrom. 1993 Nov;7(11):1041-7. doi: 10.1002/rcm.1290071115.
A number of different low molecular weight and volatile compounds have been tested and compared as matrices in 252Cf plasma-desorption mass spectrometry (PDMS) measurements of oligosaccharides. Some heteroaromatic amines (2-aminothiazole and 3-aminopyridine), hydroxyanthraquinones (alizarin and quinalizarin) and phthaleins (fluorescein) proved to be especially suited to enhancing the quasimolecular ion intensity of oligosaccharides. Discrimination effects could be reduced by matrix addition and thus, quantitative results of PDMS could be improved. Oligosaccharides with broad molecular weight distribution (dextrin 10 and dextran T 1.5) have been successfully analyzed by PDMS. The mass spectra obtained compared quite well with ion chromatograms of the respective oligosaccharides.
在对寡糖进行的²⁵²Cf等离子体解吸质谱（PDMS）测量中，已对多种不同的低分子量挥发性化合物作为基质进行了测试和比较。一些杂环芳胺（2-氨基噻唑和3-氨基吡啶）、羟基蒽醌（茜素和奎诺茜素）和酞类化合物（荧光素）被证明特别适合增强寡糖的准分子离子强度。通过添加基质可以减少歧视效应，从而改善PDMS的定量结果。具有宽分子量分布的寡糖（糊精10和葡聚糖T 1.5）已通过PDMS成功分析。所获得的质谱与相应寡糖的离子色谱图相当吻合。
