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[1例睾丸癌患者通过顺铂、依托泊苷和博来霉素联合化疗取得完全缓解,并接受了挽救性手术]

[A case of testicular cancer in which complete response was achieved with chemotherapy including cisplatin, etoposide and bleomycin, and salvage surgery].

作者信息

Uekado Y, Matsumoto M, Inagaki T, Shintani Y

机构信息

Dept. of Urology, Wakayama Medical College.

出版信息

Gan To Kagaku Ryoho. 1994 Mar;21(4):543-6.

PMID:7510465
Abstract

A 27-year-old man was admitted with a complaint of induration of the left testis in August, 1992. On physical examination, he had a palpable supraclavicular mass. The clinical diagnosis was testicular cancer with metastases of lung field, cervical, mediastinal and retroperitoneal lymph node. The histological diagnosis made by inguinal orchiectomy was embryonal cell carcinoma with syncytiotrophoblastic cell. Chemotherapy with cisplatin, etoposide and bleomycin (BEP) was started on August 22, 1992. After 3 courses of chemotherapy, most of the lymph node metastases decreased in volume on CT scan with negative tumor markers. In an attempt to obtain surgical complete response, dissection including cervical, mediastinal and retroperitoneal node was performed in December, 1992. Pathological examination revealed no viable cells in all sections. He is alive with no evidence of disease on September 8, 1993.

摘要

一名27岁男性于1992年8月因左侧睾丸硬结入院。体格检查时,可触及锁骨上肿块。临床诊断为睾丸癌伴肺野、颈部、纵隔及腹膜后淋巴结转移。经腹股沟睾丸切除术作出的组织学诊断为胚胎性细胞癌伴合体滋养层细胞。1992年8月22日开始使用顺铂、依托泊苷和博来霉素(BEP)进行化疗。3个疗程化疗后,CT扫描显示大部分淋巴结转移灶体积缩小,肿瘤标志物呈阴性。为实现手术完全缓解,于1992年12月对颈部、纵隔及腹膜后淋巴结进行了清扫。病理检查显示所有切片均无存活细胞。1993年9月8日,他存活且无疾病证据。

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