Hao X K
Tangdu Hospital, Fourth Medical College Xian.
Zhonghua Yi Xue Za Zhi. 1993 Nov;73(11):655-7, 700.
69 patients with prostatic cancer were subjected to radioimmunodetection (RAID) with 131I-labeled antibody against gamma-seminoprotein (gamma-Sm), the images of malignant tumor sites was obtained by single photon emission computed tomography (SPECT) with dual radionuclide and computer processing. Of the 69 patients 66 were confirmed by RAID. The ratio of tumor tissue to normal tissue (T/N) 6.9 and the best time for incaging was 96 hours after injection of anti-gamma-Sm. The diameter of the minimum tumor in RAID was 0.5 cm. metastatic prostatic cancer in the pelvis or bone location as well as the origin tumors were also detected in 13 cases. Anti-gamma-SmRAID can differentiate benign from malignant prostatic neoplasms. In 37 cases of benign prostate hyperplasia, only two were positive. The positive detective rate of B-ultrasound and CT was 70.8% and 73.1% respectively.
69例前列腺癌患者接受了用131I标记的抗γ-精蛋白（γ-Sm）抗体进行的放射免疫检测（RAID），通过双放射性核素单光子发射计算机断层扫描（SPECT）和计算机处理获得恶性肿瘤部位的图像。69例患者中66例经RAID确诊。肿瘤组织与正常组织的比值（T/N）为6.9，最佳显像时间为注射抗γ-Sm后96小时。RAID中最小肿瘤直径为0.5 cm。13例患者还检测到盆腔或骨部位的转移性前列腺癌以及原发肿瘤。抗γ-Sm RAID可区分前列腺良性和恶性肿瘤。在37例良性前列腺增生患者中，仅2例呈阳性。B超和CT的阳性检出率分别为70.8%和73.1%。
