Goodless D R, Viciana A L, Pardo R J, Ruiz P
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, FL 33101.
J Am Acad Dermatol. 1994 May;30(5 Pt 2):866-9. doi: 10.1016/s0190-9622(94)70101-6.
We performed an immunohistochemical analysis of a skin lesion from a patient with AIDS who had borderline tuberculoid Hansen's disease. We also evaluated other laboratory features and performed peripheral blood flow cytometric analysis. The in situ immunologic response to Mycobacterium leprae was minimally affected by concomitant infection and immunosuppression by HIV. The skin demonstrated the typical characteristics of borderline tuberculoid lesions. These results indicate that although a patient with HIV infection may have laboratory evidence typical of the immunosuppression seen in AIDS, the immunologic response to M. leprae is essentially unchanged.
我们对一名患有边缘性结核样型麻风病的艾滋病患者的皮肤病变进行了免疫组织化学分析。我们还评估了其他实验室特征，并进行了外周血流式细胞术分析。对麻风分枝杆菌的原位免疫反应受HIV合并感染和免疫抑制的影响极小。皮肤表现出边缘性结核样病变的典型特征。这些结果表明，尽管HIV感染患者可能有艾滋病中所见免疫抑制的典型实验室证据，但对麻风分枝杆菌的免疫反应基本未变。
