Takaku F
National Medical Center, Tokyo, Japan.
Oncology. 1994 Mar-Apr;51(2):123-8. doi: 10.1159/000227326.
As the introduction to a special issue of Oncology on the role of cytokines for cancer treatment, this article summarizes their various current uses. Interferons, interleukin-2 and hematopoietic factors are extensively used for the treatment of hematopoietic as well as nonhematopoietic malignancies, either as the main therapeutic agents or as an adjuvant. Combined usage of several cytokines, or cytokines and chemotherapeutic agents has been tried. Research on gene therapy using cytokines is in progress and expected to become a future modality of cytokine usage in cancer treatment.
作为《肿瘤学》关于细胞因子在癌症治疗中作用的特刊引言，本文总结了它们目前的各种用途。干扰素、白细胞介素-2和造血因子广泛用于治疗造血系统以及非造血系统恶性肿瘤，既作为主要治疗药物，也作为辅助药物。已经尝试了几种细胞因子联合使用，或细胞因子与化疗药物联合使用。使用细胞因子的基因治疗研究正在进行中，有望成为未来癌症治疗中细胞因子使用的一种方式。
