Cuschieri A, Shimi S M, Crosthwaite G, Joypaul V
Department of Surgery, Ninewells Hospital & Medical School, University of Dundee, UK.
J R Coll Surg Edinb. 1994 Feb;39(1):44-7.
The technique of bilateral total splanchnicectomy performed through a posterior thoracoscopic approach is described. The advantages of this route include excellent visual exposure of the neural anatomy of the sympathetic and avoidance of single lung anaesthesia. The procedure was performed for the relief of intractable pain in patients with advanced pancreatic cancer (n = 3) and patients suffering from chronic pancreatitis (n = 5). Persistent relief of pain until death was obtained in the patients with pancreatic cancer (2, 4, 6 months). In patients with chronic pancreatitis, the benefit to date has varied with the severity of the disease. In two patients with severe advanced disease and previous percutaneous blocks, the relief of pain lasted only 3 and 5 weeks and both patients required resection for renewed intractable pain. In three patients with minimal change disease, relief of pain has been good in the short term (maximum follow-up of 8 months). Bilateral thoracoscopic total splanchnicectomy merits further evaluation in patients with pancreatic pain. No complications including hypotension have been encountered.
描述了通过后胸腔镜入路进行双侧全内脏神经切除术的技术。该路径的优点包括对交感神经的神经解剖结构有极佳的视觉暴露,以及避免单肺麻醉。该手术用于缓解晚期胰腺癌患者(n = 3)和慢性胰腺炎患者(n = 5)的顽固性疼痛。胰腺癌患者获得了直至死亡的持续性疼痛缓解(2、4、6个月)。在慢性胰腺炎患者中,迄今为止的获益因疾病严重程度而异。在两名患有严重晚期疾病且先前接受过经皮阻滞的患者中,疼痛缓解仅持续了3周和5周,两名患者均因再次出现顽固性疼痛而需要进行切除术。在三名病情变化极小的患者中,短期内疼痛缓解良好(最长随访8个月)。双侧胸腔镜全内脏神经切除术在胰腺疼痛患者中值得进一步评估。未遇到包括低血压在内的并发症。