Aiyoshi Y, Ogata E
Endocrinol Jpn. 1978 Dec;25(6):623-9. doi: 10.1507/endocrj1954.25.623.
A 57-year old woman with thyroid carcinoma manifesting overt thyrotoxicosis is presented. After the patient had been made euthyroid with propylthiouracil, right lobectomy and lymph node dissection were performed. Permanent paraffin sections revealed follicular adenocarcinoma with capsular and vascular invasion. Metastases to the right humerus, both femurs, the skull and pleural cavity became prominent with the recurrence of thyrotoxicosis and the patient died 2 years and 3 months after operation. The clinical evidence indicates that thyrotoxicosis in the present case is caused by the excessive secretion of thyroid hormone by both the original carcinoma and the secondary deposits. Twenty three similar cases reported in the English and Japanese literatures are summarized.
本文报告一例57岁患有甲状腺癌并表现为显性甲状腺毒症的女性患者。在患者使用丙硫氧嘧啶达到甲状腺功能正常后，进行了右叶切除术和淋巴结清扫术。永久性石蜡切片显示为具有包膜和血管侵犯的滤泡性腺癌。随着甲状腺毒症的复发，右肱骨、双侧股骨、颅骨和胸腔出现转移，患者在术后2年3个月死亡。临床证据表明，本例甲状腺毒症是由原发性癌和继发性转移灶过度分泌甲状腺激素所致。总结了英文和日文文献中报道的23例类似病例。
