Smith M C
Section of Clinical Neurophysiology, Rush-Presbyterian-St Luke's Medical Center, Chicago, Illinois.
Drugs. 1994 Jun;47(6):933-44. doi: 10.2165/00003495-199447060-00006.
The majority of all febrile seizures represent a benign syndrome that does not require extensive testing or long term medication. A careful history of the febrile seizure, family history, developmental history and physical examination can identify those infants and children with this syndrome. While one-third of this group will experience additional febrile seizures, there is no significant increase in the incidence of later epilepsy or neurological sequelae. The parents of these children need to be reassured and educated about this syndrome. They should understand the emergency treatment of seizures and aggressively treat fever. The more difficult task for the physician is to correctly identify those children who experience nonbenign seizures. Careful history and physical examination can accurately identify this group. Further evaluation including neuroimaging, electroencephalogram and developmental assessment may be necessary. In those children with a high risk of later epilepsy, treatment with an antiepileptic drug should be considered.
大多数热性惊厥属于良性综合征,无需进行广泛检查或长期用药。详细了解热性惊厥病史、家族史、发育史并进行体格检查,可识别患有该综合征的婴幼儿及儿童。虽然这一群体中有三分之一会再次发生热性惊厥,但后期癫痫或神经后遗症的发生率并无显著增加。需要让这些孩子的家长放心,并对该综合征进行教育。他们应了解惊厥的急救处理方法,并积极治疗发热。对医生来说,更具挑战性的任务是正确识别那些发生非良性惊厥的儿童。通过详细的病史和体格检查能够准确识别出这一群体。可能需要进一步评估,包括神经影像学检查、脑电图检查和发育评估。对于那些后期癫痫风险较高的儿童,应考虑使用抗癫痫药物进行治疗。