Biagioni E, Bartalena L, Boldrini A, Cioni G, Giancola S, Ipata A E
Stella Maris Scientific Institute, University of Pisa, Italy.
Electroencephalogr Clin Neurophysiol. 1994 Sep;91(3):154-62. doi: 10.1016/0013-4694(94)90065-5.
The aim of this study is to identify normal EEG patterns of preterm infants, characteristic of early postmenstrual ages (PMAs). Quantitative features of EEG background activity have been examined in records from 83 preterm infants within the first 2 weeks of life at a PMA of 27-34 weeks. These subjects presented different cranial ultrasound findings and different outcomes. EEG quantitative data have been compared to the subsequent neurological evolution. We supposed that the features of EEG background activity which were associated with a favourable outcome should be considered as indexes of "normality" of the tracing for that specific PMA. At 27-30 weeks of PMA a high incidence of "temporal sawtooth," a particular rhythmic theta activity detectable in temporal regions, relates to a favourable evolution, therefore it can be assumed that this activity is a normal feature of EEG tracings at this age. On the contrary, a significant correlation between a high incidence of "temporal sawtooth" and an abnormal outcome is observable at 33-34 weeks and leads us to deduce that this pattern should disappear at this time. After 31 weeks other parameters (such as the incidence of 8-20 Hz activities, the length of the intervals and burst duration) show a significant correlation with the outcome.
本研究的目的是确定早产儿在月经龄（PMA）早期的正常脑电图模式。在83例PMA为27 - 34周的早产儿出生后2周内的脑电图记录中，对脑电图背景活动的定量特征进行了检查。这些受试者呈现出不同的头颅超声检查结果和不同的预后。脑电图定量数据已与随后的神经发育情况进行了比较。我们认为，与良好预后相关的脑电图背景活动特征应被视为该特定PMA时脑电图描记“正常”的指标。在PMA为27 - 30周时，“颞部锯齿波”（一种在颞区可检测到的特定节律性θ活动）的高发生率与良好的发育相关，因此可以认为这种活动是该年龄段脑电图描记的正常特征。相反，在33 - 34周时，可观察到“颞部锯齿波”的高发生率与异常预后之间存在显著相关性，这使我们推断这种模式在此时应消失。31周后，其他参数（如8 - 20Hz活动的发生率、间隔长度和爆发持续时间）与预后显示出显著相关性。
