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[关于根据神经系统兴奋性阈值选择的大鼠纹状体和下丘脑糖皮质激素受体的特性]

[The properties of the glucocorticoid receptors in the striatum and hypothalamus of rats selected for the threshold of excitability of their nervous systems].

作者信息

Shaliapina V G, Efimov S V, Vaĭdo A I, Lopatina N G, Rakitskaia V V, Shiriaeva N V

出版信息

Fiziol Zh Im I M Sechenova. 1994 Jan;80(1):41-6.

PMID:7522767
Abstract

In rats selected by their threshold sensitivity to electrical current, linear differences were found both at the receptor level and in stress-reactivity, the receptor lability being very high in the rats highly sensitive to electricity. The lower sensitivity rats were found to be more conservative in these parameters. The role of the hypothalamus and striatum in regulation of the hypophyseal-adrenocortical system through a feed-back mechanism, is discussed.

摘要

在根据对电流的阈值敏感性挑选出的大鼠中,在受体水平和应激反应方面均发现了线性差异,对电高度敏感的大鼠其受体不稳定性非常高。发现低敏感性大鼠在这些参数方面更为保守。本文讨论了下丘脑和纹状体通过反馈机制对垂体 - 肾上腺皮质系统的调节作用。

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