Fischer J H, Freres H, Grundmann R, Isselhard W
Chir Forum Exp Klin Forsch. 1978(1978):281-5.
In experiments on canine kidneys, cortical edema formation during hypothermic storage following a period of normothermic ischemia of up to 30 min duration was - according to the osmolality of the perfusion fluid - lower after flush perfusion with Sacks II solution than with Biotest-"Collins" solution or Ringer-mannitol solution, which resulted in the highest edema. The adenine nucleotide content fell corresponding to the duration of the hypothermic storage or the duration of an initial normothermic ischemia, but only small further changes were found during storage following initial normothermic damage. Moreover, with respect to the maintenance of nucleotide contents the strong hyperosmolar intracellular solutions were not superior to Ringer-mannitol solution of 330 mosmol/liter.
在犬肾实验中，在长达30分钟的常温缺血期后进行低温保存期间，根据灌注液的渗透压，用萨克斯II溶液冲洗灌注后的皮质水肿形成低于用比奥泰斯特 - “柯林斯”溶液或林格 - 甘露醇溶液冲洗灌注后的情况，后者导致的水肿最高。腺嘌呤核苷酸含量随着低温保存时间或初始常温缺血时间的延长而下降，但在初始常温损伤后的保存期间仅发现微小的进一步变化。此外，就核苷酸含量的维持而言，强高渗细胞内溶液并不优于330毫渗摩尔/升的林格 - 甘露醇溶液。
