Tobe T, Takahashi K, Ohkuma H, Uyama M
Department of Ophthalmology, Kansai Medical University, Osaka, Japan.
Nippon Ganka Gakkai Zasshi. 1994 Sep;98(9):837-45.
We successfully produced, highly (78%) reproducible experimental choroidal neovascularization (ChNV) in the subretinal space of pigmented rats with intense diode laser photocoagulation. ChNV in the pigmented rat was characterized by rapid development of neovascular membrane and proliferation of retinal pigment epithelium in the subretinal space. This procedure may be useful as an experimental model for ChNV.
我们通过强二极管激光光凝在色素沉着大鼠的视网膜下间隙成功产生了高度(78%)可重复的实验性脉络膜新生血管(ChNV)。色素沉着大鼠的ChNV表现为新生血管膜迅速形成以及视网膜下间隙视网膜色素上皮细胞增殖。该方法可能作为ChNV的一种实验模型。