Garelli S, Valbonesi M, Picerno G, Vazzana A
Quad Sclavo Diagn. 1978 Sep;15(3):311-5.
Among the sera of 1011 blood donors, they have been collected 34 anti-Wr(a) antibodies. By IgG antiglobulin test, the titer was 1/8 or more in 21 sera. After absorption on viral, bacterial and mycotic antigens, the sera were still reactive with Wr(a) + red blood cells. These results show that no tested antigen is cross-reactive with Wr(a) antigen. However, the AA. suggest that the research of a widley diffused antigen, cross-reactive with Wr(a) + red blood cells, is a valuable approach to the problem of IgG anti-Wr(a) antibodies in normal, never transfused blood donors.
在1011名献血者的血清中，共收集到34份抗Wr(a)抗体。通过IgG抗球蛋白试验，21份血清的效价为1/8或更高。在经病毒、细菌和真菌抗原吸收后，这些血清仍与Wr(a)+红细胞发生反应。这些结果表明，所检测的抗原与Wr(a)抗原无交叉反应。然而，作者们认为，研究一种与Wr(a)+红细胞发生交叉反应的广泛分布的抗原，是解决正常、从未输血的献血者中IgG抗Wr(a)抗体问题的一种有价值的方法。
