Angelucci E
Divisione Ematologica, Ospedale di Pesaro, Italy.
Haematologica. 1994 Jul-Aug;79(4):353-5.
The presence of anti-HCV antibodies has been examined in a group of 256 consecutive thalassemic patients who received blood transfusions in several countries around the world. Overall 60% were found to be anti-HCV positive. A higher incidence of anti-HCV antibodies was noted in Italian patients with respect to patients living in Eastern countries, and in southern Italy with respect to northern Italy. Because these patients received a large portion of their transfusions before the anti-HCV test became available, these data indicate a higher anti-HCV seroprevalence among Italian blood donors and confirm published data indicating a higher seroprevalence in southern Italy. The anti-seropositivity correlated highly with serum transaminase elevation and with histological diagnoses of chronic active hepatitis.
对一组连续的256名地中海贫血患者进行了抗丙型肝炎病毒（HCV）抗体检测，这些患者在世界多个国家接受过输血治疗。总体而言，发现60%的患者抗HCV呈阳性。与生活在东方国家的患者相比，意大利患者中抗HCV抗体的发生率更高；与意大利北部患者相比，意大利南部患者中该抗体的发生率更高。由于这些患者在抗HCV检测可用之前接受了大量输血，这些数据表明意大利献血者中抗HCV血清阳性率更高，并证实了已发表的数据，即意大利南部的血清阳性率更高。抗血清阳性与血清转氨酶升高以及慢性活动性肝炎的组织学诊断高度相关。
