Buchholz N P, Mattarelli G
Urologische Klinik Kantonsspital Basel/Schweiz.
Z Gerontol. 1994 Sep-Oct;27(5):334-6.
Orchiectomy is a frequently performed therapy for prostatic carcinoma in elderly men. A so far widely neglected side-effect is the occurrence of hot flushes. They considerably decrease the quality of life of a large number of the patients who often are in a palliative situation and handicapped by other diseases. Therapeutic options are widely unknown. Therefore, the patients often consult their doctors in vain. In a study with 32 patients clinical appearance of hot flushes and their effects on the patient's quality of life were analyzed. 69% of patients with a mean age of 75 years experienced hot flushes, whereas 31% of patients with a mean age of 80 years had not been bothered by hot flushes. Possible therapeutic options are presented and discussed. Ciproteronacetate seems to be the most effective therapy with the least side-effects (9).
睾丸切除术是老年男性前列腺癌常用的治疗方法。潮热是一种至今广泛被忽视的副作用。潮热会显著降低大量患者的生活质量，这些患者通常处于姑息治疗阶段且因其他疾病而行动不便。治疗方案鲜为人知。因此，患者常常徒劳地咨询医生。在一项针对32名患者的研究中，分析了潮热的临床表现及其对患者生活质量的影响。平均年龄75岁的患者中有69%经历过潮热，而平均年龄80岁的患者中有31%未受到潮热困扰。文中介绍并讨论了可能的治疗方案。醋酸环丙孕酮似乎是副作用最小且最有效的治疗方法（9）。
